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Human Recombinant Tau-441

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2011503 (50 µg)
Human Recombinant Tau-441 is a high quality full length human Tau-441 protein expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

Human Recombinant Tau-441
Catalog number: B2011503
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 45.8 kDa
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Tau (Tau-441), human recombinant
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Ahmad W Dr, Shabbiri K Dr, Ahmad I. Prediction of human tau 3D structure, and interplay between O-β-GlcNAc and phosphorylation modifications in Alzheimer’s disease: C. elegans as a suitable model to study these interactions in vivo Biochem Biophys Res Commun. 2020 Jul 30;528(3):466-472.
2: Karikari TK, Keeling S, Hill E, Lantero Rodrı Guez J, Nagel DA, Becker B, Höglund K, Zetterberg H, Blennow K, Hill EJ, Moffat KG. Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional Biochemistry ACS Chem Neurosci. 2020 Oct 7;11(19):3117-3129.
3: Banks WA, Kovac A, Majerova P, Bullock KM, Shi M, Zhang J. Tau Proteins Cross the Blood-Brain Barrier J Alzheimers Dis. 2017;55(1):411-419.
4: Loeffler DA, Klaver AC, Coffey MP. ELISA measurement of specific antibodies to phosphorylated tau in intravenous immunoglobulin products Int Immunopharmacol. 2015 Oct;28(2):1108-12.
5: Wang JZ, Grundke-Iqbal I, Iqbal K. Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration Eur J Neurosci. 2007 Jan;25(1):59-68.
6: Liu F, Iqbal K, Grundke-Iqbal I, Gong CX. Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta FEBS Lett. 2002 Oct 23;530(1-3):209-14.
7: Loeffler DA, Smith LM, Klaver AC, Martić S. Effects of antibodies to phosphorylated and non-phosphorylated tau on in vitro tau phosphorylation at Serine-199: Preliminary report Exp Gerontol. 2015 Jul;67:15-8.
8: Zhao H, Zhao W, Lok K, Wang Z, Yin M. A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2 Cell Mol Neurobiol. 2014 Apr;34(3):369-78.
9: Tatebayashi Y, Haque N, Tung YC, Iqbal K, Grundke-Iqbal I. Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport J Cell Sci. 2004 Apr 1;117(Pt 9):1653-63.
10: Camilleri A, Zarb C, Caruana M, Ostermeier U, Ghio S, Högen T, Schmidt F, Giese A, Vassallo N. Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols Biochim Biophys Acta. 2013 Nov;1828(11):2532-43.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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