Human Recombinant DJ-1 (PARK7)


Catalog Number: B2011234 (10 µg)
Human Recombinant DJ-1 (PARK7) is a high quality full length human DJ-1 protein (PARK7, Parkinson disease protein 7) expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2011234 Categories: ,


Human Recombinant DJ-1 (PARK7)
Catalog number: B2011234
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 19.9 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: PARK 7
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Hijioka M, Inden M, Yanagisawa D, Kitamura Y. DJ-1/PARK7: A New Therapeutic Target for Neurodegenerative Disorders Biol Pharm Bull. 2017;40(5):548-552.
2: Kim DK, Beaven MA, Metcalfe DD, Olivera A. Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells J Allergy Clin Immunol. 2018 Jul;142(1):195-206.e8.
3: Saito Y, Miyasaka T, Hatsuta H, Takahashi-Niki K, Hayashi K, Mita Y, Kusano-Arai O, Iwanari H, Ariga H, Hamakubo T, Yoshida Y, Niki E, Murayama S, Ihara Y, Noguchi N. Immunostaining of oxidized DJ-1 in human and mouse brains J Neuropathol Exp Neurol. 2014 Jul;73(7):714-28.
4: Bahmed K, Boukhenouna S, Karim L, Andrews T, Lin J, Powers R, Wilson MA, Lin CR, Messier E, Reisdorph N, Powell RL, Tang HY, Mason RJ, Criner GJ, Kosmider B. The effect of cysteine oxidation on DJ-1 cytoprotective function in human alveolar type II cells Cell Death Dis. 2019 Sep 2;10(9):638.
5: Inden M, Taira T, Kitamura Y, Yanagida T, Tsuchiya D, Takata K, Yanagisawa D, Nishimura K, Taniguchi T, Kiso Y, Yoshimoto K, Agatsuma T, Koide-Yoshida S, Iguchi-Ariga SM, Shimohama S, Ariga H. PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson’s disease rat model Neurobiol Dis. 2006 Oct;24(1):144-58.
6: Fang M, Zhong XY, Du B, Lin CL, Luo F, Tang LJ, Chen J. Role of DJ-1-induced PTEN down-regulation in migration and invasion of human glioma cells Chin J Cancer. 2010 Dec;29(12):988-94.
7: Song IK, Kim MS, Ferrell JE Jr, Shin DH, Lee KJ. Stepwise oxidations play key roles in the structural and functional regulations of DJ-1 Biochem J. 2021 Oct 15;478(19):3505-3525.
8: Taira T, Takahashi K, Kitagawa R, Iguchi-Ariga SM, Ariga H. Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter Gene. 2001 Jan 24;263(1-2):285-92.
9: Prahlad J, Hauser DN, Milkovic NM, Cookson MR, Wilson MA. Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers J Neurochem. 2014 Sep;130(6):839-53.
10: Sekito A, Taira T, Niki T, Iguchi-Ariga SM, Ariga H. Stimulation of transforming activity of DJ-1 by Abstrakt, a DJ-1-binding protein Int J Oncol. 2005 Mar;26(3):685-9.

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