Human PLK3 Protein Active

Description

Human PLK3 Protein Active
Catalog number: B2014016
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μg
Molecular Weight or Concentration: 36 kDa
Supplied as: N/A
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: PLK3 Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Aquino Perez C, Palek M, Stolarova L, von Morgen P, Macurek L. Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6 Cells. 2020 Jun 20;9(6):1506.
2: Helmke C, Becker S, Strebhardt K. The role of Plk3 in oncogenesis Oncogene. 2016 Jan 14;35(2):135-47.
3: Sang M, Ando K, Okoshi R, Koida N, Li Y, Zhu Y, Shimozato O, Geng C, Shan B, Nakagawara A, Ozaki T. Plk3 inhibits pro-apoptotic activity of p73 through physical interaction and phosphorylation Genes Cells. 2009 Jul;14(7):775-88.
4: Xu D, Dai W, Li C. Polo-like kinase 3, hypoxic responses, and tumorigenesis Cell Cycle. 2017;16(21):2032-2036.
5: Deng W, Wei X, Xie Z, Zhang R, Dong Z, Zhang J, Luo Y, Cheng Q, Wang R, Li H, Na N. Inhibition of PLK3 Attenuates Tubular Epithelial Cell Apoptosis after Renal Ischemia-Reperfusion Injury by Blocking the ATM/P53-Mediated DNA Damage Response Oxid Med Cell Longev. 2022 Jun 24;2022:4201287.
6: Xu D, Yao Y, Lu L, Costa M, Dai W. Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha J Biol Chem. 2010 Dec 10;285(50):38944-50.
7: Wang H, Tian C, Fan XY, Chen LN, Lv Y, Sun J, Zhao YJ, Zhang LB, Wang J, Shi Q, Gao C, Chen C, Shao QX, Dong XP. Polo-like kinase 3 (PLK3) mediates the clearance of the accumulated PrP mutants transiently expressed in cultured cells and pathogenic PrP(Sc) in prion infected cell line via protein interaction Int J Biochem Cell Biol. 2015 May;62:24-35.
8: Wang H, Tian C, Sun J, Chen LN, Lv Y, Yang XD, Xiao K, Wang J, Chen C, Shi Q, Shao QX, Dong XP. Overexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated Autophagy Mol Neurobiol. 2017 Aug;54(6):4401-4413.
9: Xie S, Wu H, Wang Q, Kunicki J, Thomas RO, Hollingsworth RE, Cogswell J, Dai W. Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2 Cell Cycle. 2002 Nov-Dec;1(6):424-9.
10: Bahassi el M, Conn CW, Myer DL, Hennigan RF, McGowan CH, Sanchez Y, Stambrook PJ. Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways Oncogene. 2002 Sep 26;21(43):6633-40.

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