Human Factor XII
Catalog Number: B2014018 (0.5 mg)
Human Factor XII is a high quality Purified from fresh frozen human plasma. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Live enquiry about this product via Text/SMS: 1-858-900-3210.
Human Factor XII
Catalog number: B2014018
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mg
Molecular Weight or Concentration: 80 kDa
Supplied as: N/A
Applications: molecular tool for various biochemical applications
Keywords: Human Factor XII
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
1: Citarella F, Misiti S, Felici A, Farsetti A, Pontecorvi A, Fantoni A. Estrogen induction and contact phase activation of human_factor XII Steroids. 1996 Apr;61(4):270-6.
2: Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renn T. An update on factor XII-driven vascular inflammation Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166.
3: Peng B, Xue G, Xu D, Feng Z, Chen J, Huang M, Lu H, Gong L. Expression and purification of recombinant serine protease domain of human coagulation factor XII in Pichia pastoris Biosci Biotechnol Biochem. 2019 Oct;83(10):1815-1821.
4: Griffin JH, Cochrane CG. Human factor XII (Hageman factor) Methods Enzymol. 1976;45:56-65.
5: Samuel M, Pixley RA, Villanueva MA, Colman RW, Villanueva GB. Human factor XII (Hageman factor) autoactivation by dextran sulfate. Circular dichroism, fluorescence, and ultraviolet difference spectroscopic studies J Biol Chem. 1992 Sep 25;267(27):19691-7.
6: Kalinin DV. Factor XII(a) inhibitors: a review of the patent literature Expert Opin Ther Pat. 2021 Dec;31(12):1155-1176.
7: de Maat S, Clark CC, Boertien M, Parr N, Sanrattana W, Hofman ZLM, Maas C. Factor XII truncation accelerates activation in solution J Thromb Haemost. 2019 Jan;17(1):183-194.
8: Pixley RA, Colman RW. Purification of human factor XII from plasma using zinc chelate affinity chromatography Thromb Res. 1986 Jan 1;41(1):89-98.
9: Shamanaev A, Litvak M, Gailani D. Recent advances in factor XII structure and function Curr Opin Hematol. 2022 Sep 1;29(5):233-243.
10: Davoine C, Bouckaert C, Fillet M, Pochet L. Factor XII/XIIa inhibitors: Their discovery, development, and potential indications Eur J Med Chem. 2020 Dec 15;208:112753.
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