HIV-1 GP120 protein


Catalog Number: B2014568 (100 μg)
HIV-1 GP120 protein is a high quality recombinant human glycoprotein 120 (gp120) expressed in human HEK 293 cells as an C-terminally his-tagged. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2014568 Categories: , Tag:


HIV-1 GP120 protein
Catalog number: B2014568
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 μg
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Glycoprotein 120 (gp120), Surface protein gp120
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Jacquemard C, Koensgen F, Colin P, Lagane B, Kellenberger E. Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor Viruses. 2021 Jul 18;13(7):1395.
2: Metlas R, Veljkovic V. HIV-1 gp120 and immune network Int Rev Immunol. 2004 Sep-Dec;23(5-6):413-22.
3: Stansell E, Panico M, Canis K, Pang PC, Bouché L, Binet D, O’Connor MJ, Chertova E, Bess J, Lifson JD, Haslam SM, Morris HR, Desrosiers RC, Dell A. Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate PLoS One. 2015 Apr 27;10(4):e0124784.
4: Kassler K, Sticht H. Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity J Biomol Struct Dyn. 2014;32(1):52-64.
5: Rathore U, Saha P, Kesavardhana S, Kumar AA, Datta R, Devanarayanan S, Das R, Mascola JR, Varadarajan R. Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity J Biol Chem. 2017 Jun 16;292(24):10197-10219.
6: Kong LY, Wilson BC, McMillian MK, Bing G, Hudson PM, Hong JS. The effects of the HIV-1 envelope protein gp120 on the production of nitric oxide and proinflammatory cytokines in mixed glial cell cultures Cell Immunol. 1996 Aug 25;172(1):77-83.
7: Parajuli B, Acharya K, Nangarlia A, Zhang S, Parajuli B, Dick A, Ngo B, Abrams CF, Chaiken I. Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate Biochem J. 2020 Nov 13;477(21):4263-4280.
8: Parajuli B, Acharya K, Bach HC, Parajuli B, Zhang S, Smith AB 3rd, Abrams CF, Chaiken I. Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus Biochem J. 2018 Mar 9;475(5):931-957.
9: Pan R, Gorny MK, Zolla-Pazner S, Kong XP. The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel J Virol. 2015 Aug;89(15):8003-10.
10: Yolitz J, Schwing C, Chang J, Van Ryk D, Nawaz F, Wei D, Cicala C, Arthos J, Fauci AS. Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120 Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2443-2448.

Products Related to HIV-1 GP120 protein can be found at Proteins

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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