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Dickkopf Related Protein-1 (Human)

$695.00 $495.00

Catalog Number: B2010350 (10 ug)
Dickkopf Related Protein-1 (Human) is a high quality research product used as highly pure Dickkopf Related Protein-1 (Human) expressed in HEK 293. This protein acts as a protein involved in embryonic development through its inhibition of the Wnt signaling pathway. Custom bulk orders of this product are available upon request.

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SKU: B2010350 Categories: , ,

Description

Dickkopf Related Protein-1 (Human)
Catalog number: B2010350
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Dickkopf Related Protein-1 (Human) expressed in HEK 293. This protein acts as a protein involved in embryonic development through its inhibition of the Wnt signaling pathway.
Storage: -20C
Keywords: rHuDKK-1; hDkk-1; SK
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Menet R, Bourassa P, Calon F, ElAli A. Dickkopf-related protein-1 inhibition
attenuates amyloid-beta pathology associated to Alzheimer’s disease. Neurochem
Int. 2020 Dec;141:104881.

2: Auziņa D, Beinaroviča I, Janicka-Kupra B, Lejniece S, Lejnieks A, Groma V.
Dickkopf-related protein 1 expression in bone marrow of multiple myeloma
patients: correlation with bone disease and plasma cell malignancy type. Exp
Oncol. 2020 Dec;42(4):285-288.

3: Jiang SJ, Jin ZZ, Peng YJ. Expression of Dickkopf-related Protein 1 in
Patients with Temporomandibular Osteoarthritis after Treatment with Hyaluronic
Acid. Curr Med Sci. 2020 Jun;40(3):574-579.

4: Sui Q, Zheng J, Liu D, Peng J, Ou Q, Tang J, Li Y, Kong L, Jiang W, Xiao B,
Chao X, Pan Z, Zhang H, Ding PR. Dickkopf-related protein 1, a new biomarker for
local immune status and poor prognosis among patients with colorectal liver
Oligometastases: a retrospective study. BMC Cancer. 2019 Dec 12;19(1):1210.

5: Huang X, Zhong L, van Helvoort E, Lafeber F, Mastbergen S, Hendriks J, Post
JN, Karperien M. The Expressions of Dickkopf-Related Protein 1 and Frizzled-
Related Protein Are Negatively Correlated to Local Inflammation and
Osteoarthritis Severity. Cartilage. 2019 Apr 4:1947603519841676.

6: Hamada-Ode K, Taniguchi Y, Shimamura Y, Fujimoto S, Terada Y. Serum dickkopf-
related protein 1 and sclerostin may predict the progression of chronic kidney
disease in Japanese patients. Nephrol Dial Transplant. 2019 Aug
1;34(8):1426-1427.

7: Xiong JH, Liu J, Chen J. Clinical significance and prognostic value of tumor
necrosis factor-α and dickkopf related protein-1 in ankylosing spondylitis.
World J Clin Cases. 2020 Apr 6;8(7):1213-1222.
8: Zhang R, Lin HM, Broering R, Shi XD, Yu XH, Xu LB, Wu WR, Liu C. Dickkopf-1
contributes to hepatocellular carcinoma tumorigenesis by activating the
Wnt/β-catenin signaling pathway. Signal Transduct Target Ther. 2019 Dec 6;4:54.

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