β-Chloro-D-alanine Hydrochloride


Catalog Number: B2014238 (50 mg)
β-Chloro-D-alanine Hydrochloride is a high quality β-Chloro-D-alanine hydrochloride. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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β-Chloro-D-alanine Hydrochloride
Catalog number: B2014238
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 160 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: β-Chloro-D-alanine hydrochloride
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Manning JM, Merrifield NE, Jones WM, Gotschlich EC. Inhibition of bacterial growth by beta-chloro-D-alanine Proc Natl Acad Sci U S A. 1974 Feb;71(2):417-21.
2: Prosser GA, Rodenburg A, Khoury H, de Chiara C, Howell S, Snijders AP, de Carvalho LP. Glutamate Racemase Is the Primary Target of _-Chloro-d-Alanine in Mycobacterium tuberculosis Antimicrob Agents Chemother. 2016 Sep 23;60(10):6091-9.
3: Nagasawa T, Ohkishi H, Kawakami B, Yamano H, Hosono H, Tani Y, Yamada H. 3-Chloro-D-alanine chloride-lyase (deaminating) of Pseudomonas putida CR 1.1. Purification and characterization of a novel enzyme occurring in 3-chloro-D-alanine-resistant pseudomonads J Biol Chem. 1982 Nov 25;257(22):13749-56.
4: Kaczorowski G, Shaw L, F-entes M, Walsh C. Coupling of alanine racemase and D-alanine dehydrogenase to active transport of amino acids in Escherichia coli B membrane vesicles J Biol Chem. 1975 Apr 25;250(8):2855-65.
5: Soper TS, Jones WM, Lerner B, Trop M, Manning JM. Inactivation of bacterial D-amino acid transaminase by beta-chloro-D-alanine J Biol Chem. 1977 May 25;252(10):3170-5.
6: Nagasawa T, Ishii T, Yamada H. Physiological comparison of D-cysteine desulfhydrase of Escherichia coli with 3-chloro-D-alanine dehydrochlorinase of Pseudomonas putida CR 1-1 Arch Microbiol. 1988;149(5):413-6.
7: David S. Synergic activity of D-cycloserine and beta-chloro-D-alanine against Mycobacterium tuberculosis J Antimicrob Chemother. 2001 Feb;47(2):203-6.
8: Kaczorowski G, Shaw L, Laura R, Walsh C. Active transport in Escherichia coli B membrane vesicles. Differential inactivating effects from the enzymatic oxidation of beta-chloro-L-alanine and beta-chloro-D-alanine J Biol Chem. 1975 Dec 10;250(23):8921-30.
9: Mobashery S, Johnston M. Inactivation of alanine racemase by beta-chloro-L-alanine released enzymatically from amino acid and peptide C10-esters of deacetylcephalothin Biochemistry. 1987 Sep 8;26(18):5878-84.
10: Whalen WA, Wang MD, Berg CM. beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase J Bacteriol. 1985 Dec;164(3):1350-2.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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