[Interpretation of pathological changes for “Guidelines for the Diagnosis and Treatment of COVID-19 by the National Health Commission (Trial Versio…
Authors of this article are:
Ding YQ, Bian XW.
A summary of the article is shown below:
in Chinese国家卫生健康委员会发布《新型冠状病毒肺炎诊疗方案(试行第七版)》,首次将病理变化纳入其中。这些病理变化信息是基于当时所获得的有限病例病理观察(重庆和武汉共7例遗体穿刺、5例系统尸检)结果,经过多名病理专家和临床专家讨论总结并达成共识,是目前较为全面的新型冠状病毒感染疾病(COVID-19)病理变化的总结,是COVID-19诊疗方案的重要指导性指标。本文根据COVID-19病理学研究结果,结合严重急性呼吸综合征(SARS)的病理变化,对两种疾病的多器官病理变化进行了比较分析,发现COVID-19与SARS导致的机体病理变化大致相同,主要病变发生在肺、免疫系统(脾脏、淋巴结)及各器官的血管,但SARS肺、脾脏及各器官的血管病变严重且广泛,而COVID-19 Ⅱ型肺泡上皮细胞的增生不如SARS显著,肺内支气管内甚至肺泡腔内可见较多支气管栓,SARS则少见,这可能是通气和换气功能障碍的直接而重要的病理基础,关于COVID-19病理变化,由于掌握的材料有限,尚需将来积累更多的尸体解剖资料予以补充,目前相关的病理变化信息仅供参考。.
Check out the article’s website on Pubmed for more information:
This article is a good source of information and a good way to become familiar with topics such as: COVID-19; SARS-COV-2; 2019-nCoV; Coronavirus.
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