Laboratory testing of extravascular body fluids: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory …

A new interesting article has been published in Biochem Med (Zagreb). 2020 Feb 15; 30(1):010502. doi: 10.11613/BM.2020.010502. Epub 2019 Dec 15. Review and titled:

Laboratory testing of extravascular body fluids: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory …

Authors of this article are:

Milevoj Kopcinovic L, Culej J, Jokic A, Bozovic M, Kocijan I.

A summary of the article is shown below:

Extravascular body fluids (EBF) analysis can provide useful information in the differential diagnosis of conditions that caused their accumulation. Their unique nature and particular requirements accompanying EBF analysis need to be recognized in order to minimize possible negative implications on patient safety. This recommendation was prepared by the members of the Working group for extravascular body fluid samples (WG EBFS). It is designed to address the total testing process and clinical significance of tests used in EBF analysis. The recommendation begins with a chapter addressing validation of methods used in EBF analysis, and continues with specific recommendations for serous fluids analysis. It is organized in sections referring to the preanalytical, analytical and postanalytical phase with specific recommendations presented in boxes. Its main goal is to assist in the attainment of national harmonization of serous fluid analysis and ultimately improve patient safety and healthcare outcomes. This recommendation is intended to all laboratory professionals performing EBF analysis and healthcare professionals involved in EBF collection and processing. Cytological and microbiological evaluations of EBF are beyond the scope of this document.Croatian Society of Medical Biochemistry and Laboratory Medicine.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as: Body Fluids; Clinical Laboratory Techniques; Exudates and Transudates; Guidelines as Topic; Humans; Patient Safety; Pleural Effusion; Quality Assurance, Health Care; Societies, Medical; Specimen Handling.


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