Blog

A new interesting article has been published in Rev Soc Bras Med Trop. 2019 Jul 18;52:e20190154. doi: 10.1590/0037-8682-0154-2019. and titled:

Evaluation of DPP® and SNAP® Rapid Tests for diagnosis of Leishmania infantum canine infections.

Authors of this article are:

Souza CDSF, Silva VL, Labarthe N.

A summary of the article is shown below:

INTRODUCTION: Visceral leishmaniasis is a disease that affects humans, wildlife, and domestic species. Since dogs play a key role in urban Leishmania spp. transmission, the Brazilian government maintains the Monitoring and Control Program of Visceral Leishmaniasis (VLMCP) in endemic regions, which promotes awareness campaigns aiming to enhance the control of the infection. The VLMCP recommends the Dual Path Platform (DPP®) canine visceral leishmaniasis test (Bio-Manguinhos, Brazil) for screening and enzyme-linked immunosorbent assay to confirm the infection. The DPP® test is produced and distributed by the Health Ministry to the Municipal Health Centers responsible for the local VLMCP. The test is not available to all the clinics, forcing some veterinarians to use other rapid tests for screening and diagnosis of this disease in their daily routine.METHODS: The present study was conducted to compare the performance of the DPP® and SNAP® tests using sera from the dogs with confirmed infections of L. infantum and from the dogs with no previous testing, residing in areas with a low Leishmania infection.RESULTS: There was 97.0% agreement between the two tests. Sensitivity and specificity of the SNAP® test were 96.3% and 100%, respectively. Agreement between both the antibody tests and the parasitological detection methods was 96.8%. The DPP® test had 95.8% sensitivity and 100% specificity.CONCLUSIONS: The SNAP® and the DPP® tests were virtually equivalent in terms of detection of canine antibodies against L. infantum, and both the tests demonstrated high and similar levels of sensitivity and specificity.

Check out the article’s website on Pubmed for more information:

This article is a good source of information and a good way to become familiar with topics such as: n/a.

New Chemicals from MOLECULAR DEPOT


New Proteins from MOLECULAR DEPOT


New Antibodies from MOLECULAR DEPOT


New Research Kits from MOLECULAR DEPOT