Comparison of Holladay equivalent keratometry readings and anterior corneal surface keratometry measurements in keratoconus.

A new interesting article has been published in Int Ophthalmol. 2019 Jul;39(7):1501-1509. doi: 10.1007/s10792-018-0967-2. Epub 2018 Jun 22. Comparative Study and titled:

Comparison of Holladay equivalent keratometry readings and anterior corneal surface keratometry measurements in keratoconus.

Authors of this article are:

Saglik A, Celik H.

A summary of the article is shown below:

PURPOSE: To compare the accuracy of the anterior corneal simulated keratometry (SimK) and the Holladay equivalent keratometry reading (EKR) provided by a Scheimpflug camera (Pentacam HR) with the keratometry (K) provided by a Placido system (T-Cone topography) in keratoconus and control eyes.METHODS: This prospective study included 40 consecutive patients with keratoconus and 40 voluntary participants with no ocular complaints. Any patients with corneal scar, corneal trauma, history of corneal surgery or contact lens usage were excluded from the study. Mean SimK and Holladay EKR measurements were taken with Pentacam HR in the 2, 3, and 4.5 mm corneal zones, and these values were compared with the T-Cone mean K value with the Placido topography system attachment on the Lenstar LS 900. Statistical analysis was performed using the paired Student’s t test and the Bland-Altman analysis.RESULTS: A statistically significant difference was determined between the Placido K and the Scheimpflug EKR 2, 3, 4.5 mm and SimK values in the keratoconus group (p < 0.05). In the analyses which showed a difference between the SimK and Holladay EKR, it was observed that as the diameter of the corneal zone increased, the 95% LoA values were extended. No statistically significant difference was determined between the SimK and EKR 2 mm values (p > 0.05). In the control group, there was no statistically significant difference between any of the keratometric values.CONCLUSION: In diseases which affect the posterior corneal surface, such as keratoconus, it is thought that because of the asymmetrical peripheral placement of the corneal apex, as the corneal diameter increases there could be an error increase of 1-3 mm in keratometric systems evaluating the anterior surface.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as: Adolescent;Adult;Child;Cornea;Corneal Topography;Equipment Design;Female;Follow-Up Studies;Humans;Keratoconus;Male;Middle Aged;Prospective Studies;Refraction, Ocular;Young Adult.

New Chemicals from MOLECULAR DEPOT


New Proteins from MOLECULAR DEPOT


New Antibodies from MOLECULAR DEPOT


New Research Kits from MOLECULAR DEPOT

Molecular Depot

Your specialty peptide, proteins, antibodies and chemical compounds store.